Rare disease genetics
Identifying how disease-associated variants disrupt RNA processing.
Research
Interpretable AI for RNA therapeutic design
I build sequence models to understand splicing regulation and predict how to modify it.
Prioritizing ASOs before screening
Antisense oligonucleotide screening is costly. I use computational predictions to prioritize target sites and guide experiments that test how candidate ASOs affect splicing.
Model interpretation
Connecting predictions to sequence features and testable mechanisms.